The Goldilocks principle as it applies to perioperative blood pressure: what is too high, too low, or just right?

Blood Pressure Control in Neurological ICU Patients: What is Too High and What is Too Low?

The optimal blood pressure (BP) management in critically ill patients with neurological emergencies in the intensive care unit poses several challenges. Both over and under correction of the blood pressure are associated with increased morbidity and mortality in this population. Target blood pressures and therapeutic management are based on guidelines including those from the American Stroke As...

The Goldilocks Principle, Carbon Dioxide, and Acute Respiratory Distress Syndrome: Too Much, Too Little, or Just Right?

Anesthesiology, V 124 • No 3 532 March 2016 O N the face of it, we have blown hot, then cold when it comes to carbon dioxide. We have tolerated it (permissive hypercapnia), considered adding it (therapeutic hypercapnia), and even at times deliberately or inadvertently decreased it.1 Advances in extracorporeal therapies, as reported in this month’s ANesthesiol...

The QT interval: too long, too short or just right.

Is the Service Quality of Private Roads too Low, too High, or just Right when Firms compete Stackelberg in Capacity?

We study road supply by competing firms between a single origin and destination. In previous studies, firms simultaneously set their tolls and capacities while taking the actions of the others as given in a Nash fashion. Then, under some widely used technical assumptions, firms set a volume/capacity ratio that is socially optimal, and thus the level of travel time or service quality is socially...

Is the travel time of private roads too short , too long , or just right ? †

We consider price and service-quality setting in oligopolistic markets for congestible services, applied to the case of private roads. Previous studies show that parallel competitors set a volume/capacity ratio (and thereby a travel time or service quality) that is socially optimal if they take the actions of the others as given. We find that this result does not hold when capacity and toll set...